Vanadium Pentoxide

This chemical standard operating procedure (SOP) is for your safety. Read, understand, and follow this document. If this is a paper copy, you should check for the most recent version on the IsoLab website. This document was created from a template modeled after the University of Washington Environmental Health and Safety Laboratory Safety Manual Standard Operating Procedures Components.

Is Vanadium pentoxide a particularly hazardous substance? YES

What is a particularly hazardous substance? The University of Washington Environmental Health and Safety defines it here.

The SDS for Vanadium pentoxide can be found here.

1. Process Vanadium pentoxide is used as a combustion aid when analyzing solid material for sulfur isotopes.
2. Hazards Vanadium pentoxide (V2O5) is, harmful if swallowed or if inhaled, causes serious eye damage, may cause respiratory irritation, is suspected of causing genetic defects, is suspected of damaging fertility or the unborn child, causes damage to organs through prolonged or repeated exposure, toxic to aquatic life with long lasting effects. Refer to the SDS for more information.
3. Personal Protective Equipment While working with V2O5 in a fume hood, you should be wearing a laboratory coat and nitrile gloves. Do not work with V2O5 outside of the fume hood.
4. Environmental / Ventilation Controls V2O5 is to be used in one of the fume hoods in 303B or the fume hood in 302A. Ensure the fume hood has appropriate flow prior to working with V2O5. Do not work with V2O5 unless the fume hood is functioning properly.
5. Special Handling Procedures & Storage Requirements V2O5 is stored in the desiccator in 303B. Make sure you have your laboratory coat and gloves on before opening the desiccator. We use smaller, easier to handle, glass vial containers for routine handling of V2O5. Do not use the stock bottle when loading V2O5 into your sample tins. Close the V2O5 container with the appropriate lid when not in use.
6. Spill and Accident Procedures

All personnel without PPE should evacuate the room if there is a spill outside of the fume hood. Dust may present a serious health risk. 

Use personal protective equipment. If spill is outside of fume hood, don a respiratory mask located in 303B near the balances in addition to a laboratory coat, nitrile gloves, and goggles. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

If you need further assistance, during business hours, call EH&S at 206.543.0467 or if after hours, call 911 and ask for EH&S assistance. When necessary EH&S will obtain a chemical spill cleanup contractor at the lab’s expense. If trained and equipped, cleanup small spills only.

Spill materials are a hazardous waste. Report the spill via the EH&S Online Accident Reporting System (OARS).

If the spill occurred in and is completely contained in the fume hood, clean up all material using wipes and paper towels. Discard all materials that have come into contact with V2O5  into the designated waste container.

7. Waste Disposal All V2O5 waste is contained in an appropriate labeled tightly sealable plastic, wide-mouth, container. Do not open the waste container unless it is contained in a fume hood. Gloves used during handling should go into the waste container. Any wipes used for cleanup, must go into the waste container. The elemental analyzer ash insert should be discarded into the waste container after it is sufficiently cooled. Contact EH&S for waste removal when the container is sufficiently full or aged.
8. Special Precautions for Animal Use (if applicable) N/A
Particularly hazardous substance involved? YES, see 9-11
9. Approval Required You must have taken Managing Laboratory Chemicals or similar UW EH&S condoned course before using V2O5. You must have read and understood the SDS for V2O5 as well as this SOP.
10. Decontamination Make sure all V2O5 has been cleaned up and contained in appropriate containers before moving away from the fume hood. Ensure all utensils and trays have been wiped clean before removing them from the fume hood.
11. Designated Area V2O5 may only be used in the fume hoods in 303B or the fume hood in 302A.


I have read and understood this Chemical SOP:

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Last updated: 2020-10-13 11:43:02