This chemical standard operating procedure (SOP) is for your safety. Read, understand, and follow this document. If this is a paper copy, you should check for the most recent version on the IsoLab website. This document was created from a template modeled after the University of Washington Environmental Health and Safety Laboratory Safety Manual Standard Operating Procedures Components.

Is Methanol a particularly hazardous substance? YES

What is a particularly hazardous substance? The University of Washington Environmental Health and Safety defines it here.

The SDS for Methanol can be found here.

1. Process Methanol is used as a general solvent throughout the lab.
2. Hazards Methanol has acute toxicity, is a highly flammable liquid and vapour, is toxic if swallowed, is toxic in contact with skin, is toxic if inhaled, and causes damage to organs. Refer to the SDS for more information.
3. Personal Protective Equipment While working with methanol in a fume hood you should be wearing nitrile gloves, a lab coats, and eye protection. Do not work with methanol outside of the fume hood.
4. Environmental / Ventilation Controls Methanol is to be used in one of the fume hoods in the 302 / 303 suite. Ensure the fume hood has appropriate flow prior to working with methanol. Do not work with methanol unless the fume hood is functioning properly.
5. Special Handling Procedures & Storage Requirements Methanol is stored in the flammables cabinet under the fume hood in 302A. Make sure you have your laboratory coat, eye protection, and gloves on before handling the bottle.
6. Spill and Accident Procedures

Inside Fume Hood Spill - The fume hood should protect you from fumes. Contain the solution with absorbent materials from the spill kit and place in a suitable waste container.

Outside Fume Hood Spill - Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

7. Waste Disposal All methanol waste is contained in an appropriate labeled tightly sealable plastic, wide-mouth, container. Do not open the waste container unless it is contained in a fume hood. Contact EH&S for waste removal when the container is sufficiently full or aged.
8. Special Precautions for Animal Use (if applicable) N/A
Particularly hazardous substance involved? YES, see 9-11
9. Approval Required

You must have taken Managing Laboratory Chemicals or similar UW EH&S condoned course before using methanol. You must have read and understood the SDS for Methanol as well as this SOP. You also must review your process with previously trained laboratory personnel.

10. Decontamination Any glassware that has been used with methanol should be rinsed such that the first rinse goes into the above mentioned waste container. Subsequent rinse or washing of glassware can be done outside the fume hood in the sink as per normal lab glassware cleaning procedures.
11. Designated Area Methanol may only be used in a fume hood. Preferably the fume hood directly above its storage location.


I have read and understood this Chemical SOP:

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Last updated: 2020-10-13 11:33:05